Clinical Features:

SETTLE typically occurs in adolescents and young adults. It usually presents as a mass in the neck localized to the thyroid. Treatment has predominantly been surgical, although chemotherapy and radiation have also been used. . Surgery may be a cure, but late metastasis has been observed.

Gross Pathology:

The mass within the thyroid gland is usually lobulated, circumscribed, white to tan in color.

Microscopic Pathology:
 

The tumor is composed primarily of spindle cells, separated by bands of collagen forming lobules.  In the two micrographs above, you can see the spindle cells and if you are a little creative in your imagination, you can see the the curved formation; this is a high power picture and at this magnification we are only seeing part of the swirling pattern.